When explicitly instructed to use similar strategies, individuals with schizophrenia can significantly improve their episodic memory performance ( McClain, 1983 Ragland et al., 2003 Bonner-Jackson et al., 2005 Bonner-Jackson and Barch, 2011 Guimond and Lepage, 2016). ![]() The use of encoding strategies (e.g., forming a story, mental imagery, or using categories to link words) in non-clinical individuals often results in a richer memory-trace that subsequently increases recollection when compared to thinking about the word's visual features or using repetition ( Bower, 1970 Tulving, 1972 Craik, 2002). People with schizophrenia fail to spontaneously generate efficient strategies that improve memory recall ( Iddon et al., 1998). ![]() Future research should examine the use of other strategies, better suited for individuals with cognitive impairments like those found in schizophrenia.Įpisodic memory, one's ability to remember past events ( Tulving, 1972), is severely impaired in schizophrenia ( Feldmann et al., 2002 Berna et al., 2016), and such deficits are associated with compromised daily living activities and poor psychosocial functioning ( Lepage et al., 2014). The MoL seems to require episodic memory, working memory monitoring and executive functions, making it suboptimal for a population with impairments in all those domains. No significant memory improvement was denoted in the schizophrenia group, possibly due to participants' difficulties using the method efficiently and due to fatigue. Improvement in healthy individuals was observed for the word list (Wilcoxon effect size r = 0.15). Subsequently, five individuals with schizophrenia completed the protocol. This approach was first validated with healthy individuals ( N = 71). Then, participants had the opportunity to put into practice the newly learned MoL and were instructed to encode and recall two new lists of items using. The MoL training protocol comprised encoding and recall of two lists of items (words and images), a training session and practice with MoL. We investigated the feasibility of a short intervention using the Method of Loci (MoL), a well-known visuospatial mnemonic, to improve episodic memory recall performance in schizophrenia. 4Comprehensive Research Into Schizophrenia and Psychosis (CRISP) Group, Department of Psychiatry, Douglas Mental Health University Institute, McGill University, Montréal, QC, Canada.3Douglas Mental Health University Institute, McGill University, Montréal, QC, Canada.2Integrated Program in Neurosciences, McGill University, Montréal, QC, Canada. ![]() 1Comprehensive Research Into Schizophrenia and Psychosis (CRISP) Group, Integrated Program in Neurosciences, Douglas Mental Health University Institute, McGill University, Montréal, QC, Canada.Ana Elisa Sousa 1 Yacine Mahdid 2 Mathieu Brodeur 3 Martin Lepage 4 *
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